(13)C tracer analysis reveals the landscape of metabolic checkpoints in human CD8(+) T cell differentiation and exhaustion

INTRODUCTION: Naïve T cells remain in an actively maintained state of quiescence until activation by antigenic signals, upon which they start to proliferate and generate effector cells to initiate a functional immune response. Metabolic reprogramming is essential to meet the biosynthetic demands of...

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Detalles Bibliográficos
Autores principales: Kirchmair, Alexander, Nemati, Niloofar, Lamberti, Giorgia, Trefny, Marcel, Krogsdam, Anne, Siller, Anita, Hörtnagl, Paul, Schumacher, Petra, Sopper, Sieghart, Sandbichler, Adolf, Zippelius, Alfred, Ghesquière, Bart, Trajanoski, Zlatko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620935/
https://www.ncbi.nlm.nih.gov/pubmed/37928527
http://dx.doi.org/10.3389/fimmu.2023.1267816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620935/
https://www.ncbi.nlm.nih.gov/pubmed/37928527
http://dx.doi.org/10.3389/fimmu.2023.1267816

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