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(13)C tracer analysis reveals the landscape of metabolic checkpoints in human CD8(+) T cell differentiation and exhaustion
INTRODUCTION: Naïve T cells remain in an actively maintained state of quiescence until activation by antigenic signals, upon which they start to proliferate and generate effector cells to initiate a functional immune response. Metabolic reprogramming is essential to meet the biosynthetic demands of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620935/ https://www.ncbi.nlm.nih.gov/pubmed/37928527 http://dx.doi.org/10.3389/fimmu.2023.1267816 |