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Features of the TCR repertoire associate with patients' clinical and molecular characteristics in acute myeloid leukemia
BACKGROUND: Allogeneic hematopoietic stem cell transplant remains the most effective strategy for patients with high-risk acute myeloid leukemia (AML). Leukemia-specific neoantigens presented by the major histocompatibility complexes (MHCs) are recognized by the T cell receptors (TCR) triggering the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620936/ https://www.ncbi.nlm.nih.gov/pubmed/37928542 http://dx.doi.org/10.3389/fimmu.2023.1236514 |