Synthesis and Evaluation of 9-Aminoacridines with SARS-CoV-2 Antiviral Activity

[Image: see text] There have been relatively few small molecules developed with direct activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Two existing antimalarial drugs, pyronaridine and quinacrine, display whole cell activity against SARS-CoV-2 in A549 + ACE2 cells...

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Detalles Bibliográficos
Autores principales: Jones, Thane, Monakhova, Natalia, Guivel-Benhassine, Florence, Lepioshkin, Alexander, Bruel, Timothée, Lane, Thomas R., Schwartz, Olivier, Puhl, Ana C., Makarov, Vadim, Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620940/
https://www.ncbi.nlm.nih.gov/pubmed/37929131
http://dx.doi.org/10.1021/acsomega.3c05900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620940/
https://www.ncbi.nlm.nih.gov/pubmed/37929131
http://dx.doi.org/10.1021/acsomega.3c05900

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