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Synthesis and Evaluation of 9-Aminoacridines with SARS-CoV-2 Antiviral Activity

[Image: see text] There have been relatively few small molecules developed with direct activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Two existing antimalarial drugs, pyronaridine and quinacrine, display whole cell activity against SARS-CoV-2 in A549 + ACE2 cells...

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Detalles Bibliográficos
Autores principales:	Jones, Thane, Monakhova, Natalia, Guivel-Benhassine, Florence, Lepioshkin, Alexander, Bruel, Timothée, Lane, Thomas R., Schwartz, Olivier, Puhl, Ana C., Makarov, Vadim, Ekins, Sean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620940/ https://www.ncbi.nlm.nih.gov/pubmed/37929131 http://dx.doi.org/10.1021/acsomega.3c05900

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