Two-carbon tethered artemisinin–isatin hybrids: design, synthesis, anti-breast cancer potential, and in silico study

Eleven two-carbon tethered artemisinin–isatin hybrids (4a–k) were designed, synthesized, and evaluated for their antiproliferative activity against MCF-7, MDA-MB-231, and MDA-MB-231/ADR breast cancer cell lines, as well as cytotoxicity toward MCF-10A cells in this paper. Among them, the representati...

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Detalles Bibliográficos
Autores principales: Wang, Ruo, Huang, Renhong, Yuan, Yaofeng, Wang, Zheng, Shen, Kunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620963/
https://www.ncbi.nlm.nih.gov/pubmed/37928644
http://dx.doi.org/10.3389/fmolb.2023.1293763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620963/
https://www.ncbi.nlm.nih.gov/pubmed/37928644
http://dx.doi.org/10.3389/fmolb.2023.1293763

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