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Two-carbon tethered artemisinin–isatin hybrids: design, synthesis, anti-breast cancer potential, and in silico study
Eleven two-carbon tethered artemisinin–isatin hybrids (4a–k) were designed, synthesized, and evaluated for their antiproliferative activity against MCF-7, MDA-MB-231, and MDA-MB-231/ADR breast cancer cell lines, as well as cytotoxicity toward MCF-10A cells in this paper. Among them, the representati...
Autores principales: | Wang, Ruo, Huang, Renhong, Yuan, Yaofeng, Wang, Zheng, Shen, Kunwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620963/ https://www.ncbi.nlm.nih.gov/pubmed/37928644 http://dx.doi.org/10.3389/fmolb.2023.1293763 |
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