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Overcoming barriers: a review on innovations in drug delivery to the middle and inner ear

Despite significant advances in the development of therapeutics for hearing loss, drug delivery to the middle and inner ear remains a challenge. As conventional oral or intravascular administration are ineffective due to poor bioavailability and impermeability of the blood-labyrinth-barrier, localiz...

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Detalles Bibliográficos
Autores principales: Delaney, Derek S., Liew, Lawrence J., Lye, Joey, Atlas, Marcus D., Wong, Elaine Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620978/
https://www.ncbi.nlm.nih.gov/pubmed/37927600
http://dx.doi.org/10.3389/fphar.2023.1207141