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Block Copolymer Encapsulation of Disarib, an Inhibitor of BCL2 for Improved Chemotherapeutic Potential

[Image: see text] A chemical inhibitor of antiapoptotic protein, BCL2, known as Disarib, suffers poor solubility in aqueous environments; thereby limiting its potential as a chemotherapeutic agent. To overcome this limitation and enhance the therapeutic efficacy of Disarib, we have employed the enca...

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Detalles Bibliográficos
Autores principales: Joy, Reshma, Siddiqua, Humaira, Sharma, Shivangi, Raveendran, Manthra, John, Franklin, Hassan, Puthusserickal Abdulrahiman, Gawali, Santosh L, Raghavan, Sathees C., George, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621013/
https://www.ncbi.nlm.nih.gov/pubmed/37929147
http://dx.doi.org/10.1021/acsomega.3c05802