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Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6

OBJECTIVE: Xinyang Tablet (XYT) has emerged as a potential intervention to counter sepsis-induced myocardial dysfunction (SMID) by influencing macrophage autophagy and M2 polarization. This study aimed to unravel the underlying mechanism of XYT in sepsis-induced myocardial dysfunction (SIMD). METHOD...

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Detalles Bibliográficos
Autores principales: Luo, Yuanyuan, Li, Yuanmei, He, Liwei, Tu, Haitao, Lin, Xinfeng, Zhao, Fengli, Huang, Yusheng, Wen, Minyong, Wang, Lingjun, Yang, Zhongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621131/
https://www.ncbi.nlm.nih.gov/pubmed/37919806
http://dx.doi.org/10.1186/s13020-023-00832-7