5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

BACKGROUND: 5α-Hydroxycostic acid is a eudemane sesquiterpene that is isolated from the natural plant, Laggera alata. It exerts anti-inflammatory and anti-angiogenic effects on human breast cancer cells, but its role and underlying mechanism in choroidal neovascularization (CNV) are still unclear. W...

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Detalles Bibliográficos
Autores principales: Lei, Wulong, Xu, Huan, Yao, Hao, Li, Lanjiao, Wang, Menglei, Zhou, Xiyuan, Liu, Xueqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621151/
https://www.ncbi.nlm.nih.gov/pubmed/37914992
http://dx.doi.org/10.1186/s10020-023-00674-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621151/
https://www.ncbi.nlm.nih.gov/pubmed/37914992
http://dx.doi.org/10.1186/s10020-023-00674-x

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