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Beneficial effects of recombinant CER-001 high-density lipoprotein infusion in sepsis: results from a bench to bedside translational research project

BACKGROUND: Sepsis is characterized by a dysregulated immune response and metabolic alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL exhibits beneficial properties, such as lipopolysaccharides (LPS) scavenging, exerting anti-inflammatory effects and providing...

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Detalles Bibliográficos
Autores principales: Stasi, Alessandra, Fiorentino, Marco, Franzin, Rossana, Staffieri, Francesco, Carparelli, Sabrina, Losapio, Rosa, Crovace, Alberto, Lacitignola, Luca, Cimmarusti, Maria Teresa, Murgolo, Francesco, Stufano, Monica, Cafiero, Cesira, Castellano, Giuseppe, Sallustio, Fabio, Ferrari, Chiara, Ribezzi, Mario, Brienza, Nicola, Schirinzi, Annalisa, Di Serio, Francesca, Grasso, Salvatore, Pontrelli, Paola, Tupin, Cyrille, Barbaras, Ronald, Keyserling-Peyrottes, Constance, Crovace, Antonio, Gesualdo, Loreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621167/
https://www.ncbi.nlm.nih.gov/pubmed/37915050
http://dx.doi.org/10.1186/s12916-023-03057-5