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Tumor-associated macrophage-derived exosomes LINC01592 induce the immune escape of esophageal cancer by decreasing MHC-I surface expression

BACKGROUND: TAMs (tumor-associated macrophages) infiltration promotes the progression of esophageal cancer (EC). However, the underlying mechanisms remain unclear. METHODS: Abnormal expression of LINC01592 from EC microarrays of the TCGA database was analyzed. LINC01592 expression level was validate...

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Detalles Bibliográficos
Autores principales: Qiao, Xinwei, Cheng, Zaixing, Xue, Kaming, Xiong, Cui, Zheng, Zhikun, Jin, Xin, Li, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621170/
https://www.ncbi.nlm.nih.gov/pubmed/37915049
http://dx.doi.org/10.1186/s13046-023-02871-2