Multi-scale characterisation of homologous recombination deficiency in breast cancer

BACKGROUND: Homologous recombination is a robust, broadly error-free mechanism of double-strand break repair, and deficiencies lead to PARP inhibitor sensitivity. Patients displaying homologous recombination deficiency can be identified using ‘mutational signatures’. However, these patterns are diff...

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Detalles Bibliográficos
Autores principales: Jacobson, Daniel H., Pan, Shi, Fisher, Jasmin, Secrier, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621207/
https://www.ncbi.nlm.nih.gov/pubmed/37919776
http://dx.doi.org/10.1186/s13073-023-01239-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621207/
https://www.ncbi.nlm.nih.gov/pubmed/37919776
http://dx.doi.org/10.1186/s13073-023-01239-7

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