Synthesis and validation of click-modified NOD1/2 agonists

NOD1 and NOD2 sense small bacterial peptidoglycan fragments, often called muropeptides, that access the cytosol. These muropeptides include iE-DAP and MDP, the minimal agonists for NOD1 and NOD2, respectively. Here, we synthesized and validated alkyne-modified muropeptides, iE-DAP-Alk and MDP-Alk, f...

Descripción completa

Detalles Bibliográficos
Autores principales: Bharadwaj, Ravi, Anonick, Madison V., Jaiswal, Swati, Mashayekh, Siavash, Brown, Ashley, Wodzanowski, Kimberly A., Okuda, Kendi, Silverman, Neal, Grimes, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621468/
https://www.ncbi.nlm.nih.gov/pubmed/37828863
http://dx.doi.org/10.1177/17534259231207198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621468/
https://www.ncbi.nlm.nih.gov/pubmed/37828863
http://dx.doi.org/10.1177/17534259231207198

Ejemplares similares