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Synthesis and validation of click-modified NOD1/2 agonists

NOD1 and NOD2 sense small bacterial peptidoglycan fragments, often called muropeptides, that access the cytosol. These muropeptides include iE-DAP and MDP, the minimal agonists for NOD1 and NOD2, respectively. Here, we synthesized and validated alkyne-modified muropeptides, iE-DAP-Alk and MDP-Alk, f...

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Detalles Bibliográficos
Autores principales:	Bharadwaj, Ravi, Anonick, Madison V., Jaiswal, Swati, Mashayekh, Siavash, Brown, Ashley, Wodzanowski, Kimberly A., Okuda, Kendi, Silverman, Neal, Grimes, Catherine L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621468/ https://www.ncbi.nlm.nih.gov/pubmed/37828863 http://dx.doi.org/10.1177/17534259231207198

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