The recombinant BMP-2 loaded silk fibroin microspheres improved the bone phenotype of mild osteogenesis imperfecta mice

Osteogenesis imperfecta (OI) is an inherited congenital disorder, characterized primarily by decreased bone mass and increased bone fragility. Bone morphogenetic protein-2 (BMP-2) is a potent cytokine capable of stimulating bone formation, however, its rapid degradation and unanticipated in vivo eff...

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Detalles Bibliográficos
Autores principales: Fu, Ting, Liu, Yi, Wang, Zihan, Jing, Yaqing, Zhao, Yuxia, Shao, Chenyi, Lv, Zhe, Li, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621593/
https://www.ncbi.nlm.nih.gov/pubmed/37927786
http://dx.doi.org/10.7717/peerj.16191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621593/
https://www.ncbi.nlm.nih.gov/pubmed/37927786
http://dx.doi.org/10.7717/peerj.16191

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