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It takes a village: microbiota, parainflammation, paligenosis and bystander effects in colorectal cancer initiation

Sporadic colorectal cancer (CRC) is a leading cause of worldwide cancer mortality. It arises from a complex milieu of host and environmental factors, including genetic and epigenetic changes in colon epithelial cells that undergo mutation, selection, clonal expansion, and transformation. The gut mic...

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Detalles Bibliográficos
Autores principales: Wang, Xingmin, Undi, Ram Babu, Ali, Naushad, Huycke, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621663/
https://www.ncbi.nlm.nih.gov/pubmed/33969420
http://dx.doi.org/10.1242/dmm.048793