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Simulating clinical trials for model-informed precision dosing: using warfarin treatment as a use case

Treatment response variability across patients is a common phenomenon in clinical practice. For many drugs this inter-individual variability does not require much (if any) individualisation of dosing strategies. However, for some drugs, including chemotherapies and some monoclonal antibody treatment...

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Detalles Bibliográficos
Autores principales: Augustin, David, Lambert, Ben, Robinson, Martin, Wang, Ken, Gavaghan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621790/
https://www.ncbi.nlm.nih.gov/pubmed/37927586
http://dx.doi.org/10.3389/fphar.2023.1270443