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Simulating clinical trials for model-informed precision dosing: using warfarin treatment as a use case
Treatment response variability across patients is a common phenomenon in clinical practice. For many drugs this inter-individual variability does not require much (if any) individualisation of dosing strategies. However, for some drugs, including chemotherapies and some monoclonal antibody treatment...
Autores principales: | Augustin, David, Lambert, Ben, Robinson, Martin, Wang, Ken, Gavaghan, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621790/ https://www.ncbi.nlm.nih.gov/pubmed/37927586 http://dx.doi.org/10.3389/fphar.2023.1270443 |
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