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Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge

The murine Bordetella pertussis challenge model has been utilized in preclinical research for decades. Currently, inconsistent methodologies are employed by researchers across the globe, making it difficult to compare findings. The objective of this work was to utilize the CD-1 mouse model with two...

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Detalles Bibliográficos
Autores principales: Weaver, Kelly L., Bitzer, Graham J., Wolf, M. Allison, Pyles, Gage M., DeJong, Megan A., Dublin, Spencer R., Huckaby, Annalisa B., Gutierrez, Maria de la Paz, Hall, Jesse M., Wong, Ting Y., Warden, Matthew, Petty, Jonathan E., Witt, William T., Cunningham, Casey, Sen-Kilic, Emel, Damron, F. Heath, Barbier, Mariette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621807/
https://www.ncbi.nlm.nih.gov/pubmed/37917623
http://dx.doi.org/10.1371/journal.pone.0286925