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Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge
The murine Bordetella pertussis challenge model has been utilized in preclinical research for decades. Currently, inconsistent methodologies are employed by researchers across the globe, making it difficult to compare findings. The objective of this work was to utilize the CD-1 mouse model with two...
Autores principales: | Weaver, Kelly L., Bitzer, Graham J., Wolf, M. Allison, Pyles, Gage M., DeJong, Megan A., Dublin, Spencer R., Huckaby, Annalisa B., Gutierrez, Maria de la Paz, Hall, Jesse M., Wong, Ting Y., Warden, Matthew, Petty, Jonathan E., Witt, William T., Cunningham, Casey, Sen-Kilic, Emel, Damron, F. Heath, Barbier, Mariette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621807/ https://www.ncbi.nlm.nih.gov/pubmed/37917623 http://dx.doi.org/10.1371/journal.pone.0286925 |
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