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Rational therapeutic targets with biomolecular liquid-liquid phase separation regulating synergy: A pan-cancer analysis

Liquid-liquid phase separation (LLPS) is characterized as an ubiquitous framework for diverse biological processes including carcinogenesis and cancer progression. While targeting cancer from perspective of LLPS offers an opportunity to drug the conventionally undruggables with cancer-driving potent...

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Detalles Bibliográficos
Autores principales: Sun, Si, Wang, Wenwen, Li, Guoqing, Xiao, Man, Peng, Minggang, Cai, Jing, Wang, Zehua, Yang, Qiang, He, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621828/
https://www.ncbi.nlm.nih.gov/pubmed/37917664
http://dx.doi.org/10.1371/journal.pone.0287574