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Rational therapeutic targets with biomolecular liquid-liquid phase separation regulating synergy: A pan-cancer analysis
Liquid-liquid phase separation (LLPS) is characterized as an ubiquitous framework for diverse biological processes including carcinogenesis and cancer progression. While targeting cancer from perspective of LLPS offers an opportunity to drug the conventionally undruggables with cancer-driving potent...
Autores principales: | Sun, Si, Wang, Wenwen, Li, Guoqing, Xiao, Man, Peng, Minggang, Cai, Jing, Wang, Zehua, Yang, Qiang, He, Xiaoqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621828/ https://www.ncbi.nlm.nih.gov/pubmed/37917664 http://dx.doi.org/10.1371/journal.pone.0287574 |
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