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Confidence interval comparison: Precision of maximum likelihood estimates in LLOQ affected data

When data is derived under a single or multiple lower limits of quantification (LLOQ), estimation of distribution parameters as well as precision of these estimates appear to be challenging, as the way to account for unquantifiable observations due to LLOQs needs particular attention. The aim of thi...

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Detalles Bibliográficos
Autores principales: Bülow, Tanja, Hilgers, Ralf-Dieter, Heussen, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621850/
https://www.ncbi.nlm.nih.gov/pubmed/37917602
http://dx.doi.org/10.1371/journal.pone.0293640