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Development of a sensitive real-time quaking-induced conversion (RT-QuIC) assay for application in prion-infected blood

Efforts to prevent human-to-human transmission of variant Creutzfeldt-Jakob disease (vCJD) by contaminated blood would be aided by the development of a sensitive diagnostic test that could be routinely used to screen blood donations. As blood samples from vCJD patients are extremely rare, here we de...

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Detalles Bibliográficos
Autores principales: Thomas, Charlotte M., Salamat, M. Khalid F., de Wolf, Christopher, McCutcheon, Sandra, Blanco, A. Richard Alejo, Manson, Jean C., Hunter, Nora, Houston, E. Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621866/
https://www.ncbi.nlm.nih.gov/pubmed/37917783
http://dx.doi.org/10.1371/journal.pone.0293845