Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

Diet-related metabolic syndrome is the largest contributor to adverse health in the United States. However, the study of gene-environment interactions and their epigenomic and transcriptomic integration is complicated by the lack of environmental and genetic control in humans that is possible in mou...

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Detalles Bibliográficos
Autores principales: Wulfridge, Phillip, Davidovich, Adam, Salvador, Anna C., Manno, Gabrielle C., Tryggvadottir, Rakel, Idrizi, Adrian, Huda, M. Nazmul, Bennett, Brian J., Adams, L. Garry, Hansen, Kasper D., Threadgill, David W., Feinberg, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621921/
https://www.ncbi.nlm.nih.gov/pubmed/37871105
http://dx.doi.org/10.1371/journal.pgen.1010997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621921/
https://www.ncbi.nlm.nih.gov/pubmed/37871105
http://dx.doi.org/10.1371/journal.pgen.1010997

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