Cargando…
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation
Diet-related metabolic syndrome is the largest contributor to adverse health in the United States. However, the study of gene-environment interactions and their epigenomic and transcriptomic integration is complicated by the lack of environmental and genetic control in humans that is possible in mou...
Autores principales: | Wulfridge, Phillip, Davidovich, Adam, Salvador, Anna C., Manno, Gabrielle C., Tryggvadottir, Rakel, Idrizi, Adrian, Huda, M. Nazmul, Bennett, Brian J., Adams, L. Garry, Hansen, Kasper D., Threadgill, David W., Feinberg, Andrew P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621921/ https://www.ncbi.nlm.nih.gov/pubmed/37871105 http://dx.doi.org/10.1371/journal.pgen.1010997 |
Ejemplares similares
-
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability
por: Rizzardi, Lindsay F., et al.
Publicado: (2019) -
Improving Metabolic Health Through Precision Dietetics in Mice
por: Barrington, William T., et al.
Publicado: (2018) -
Analyzing whole genome bisulfite sequencing data from highly divergent genotypes
por: Wulfridge, Phillip, et al.
Publicado: (2019) -
Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits
por: Rizzardi, Lindsay F., et al.
Publicado: (2021) -
DIPG-42. MAPPING THE DNA METHYLATION LANDSCAPE OF DIPG REVEALS NOTABLE METHYLOME VARIABILITY RESPONSIVE TO PHARMACOLOGIC MODULATION
por: Tetens, Ashley, et al.
Publicado: (2023)