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A novel proneural function of Asense is integrated with the sequential actions of Delta-Notch, L’sc and Su(H) to promote the neuroepithelial to neuroblast transition

In order for neural progenitors (NPs) to generate distinct populations of neurons at the right time and place during CNS development, they must switch from undergoing purely proliferative, self-renewing divisions to neurogenic, asymmetric divisions in a tightly regulated manner. In the developing Dr...

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Detalles Bibliográficos
Autores principales: Martin, Mercedes, Gutierrez-Avino, Francisco, Shaikh, Mirja N., Tejedor, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621995/
https://www.ncbi.nlm.nih.gov/pubmed/37871020
http://dx.doi.org/10.1371/journal.pgen.1010991