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Interleukin-19 promotes bone resorption by suppressing osteoprotegerin expression in BMSCs in a lipopolysaccharide-induced bone loss mouse model

AIMS: Osteoporosis is characterized by decreased trabecular bone volume, and microarchitectural deterioration in the medullary cavity. Interleukin-19 (IL-19), a member of the IL-10 family, is an anti-inflammatory cytokine produced primarily by macrophages. The aim of our study was to investigate the...

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Detalles Bibliográficos
Autores principales: Dai, Zhicheng, Chen, Yanan, He, Enjun, Wang, Hongjie, Guo, Weihong, Wu, Zhenkai, Huang, Kai, Zhao, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622185/
https://www.ncbi.nlm.nih.gov/pubmed/37918438
http://dx.doi.org/10.1302/2046-3758.1211.BJR-2023-0101.R1