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Placental expanded mesenchymal-like cells (PLX-R18) for poor graft function after hematopoietic cell transplantation: A phase I study

Persistent cytopenia in the post-hematopoietic cell transplantation (HCT) setting can occur despite adequate engraftment of donor cells. PLX-R18, a placental-derived mesenchymal-like cell product, is expanded ex vivo in a 3-dimensional environment. PLX-R18 cells secrete a large array of hematopoieti...

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Detalles Bibliográficos
Autores principales: McGuirk, Joseph P., Metheny, Leland, Pineiro, Luis, Litzow, Mark, Rowley, Scott D., Avni, Batia, Tamari, Roni, Lazarus, Hillard M., Rowe, Jacob M., Sheleg, Michal, Rothenstein, Daniel, Halevy, Nitsan, Zuckerman, Tsila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622312/
https://www.ncbi.nlm.nih.gov/pubmed/37553467
http://dx.doi.org/10.1038/s41409-023-02068-3