epialleleR: an R/Bioconductor package for sensitive allele-specific methylation analysis in NGS data

Low-level mosaic epimutations within the BRCA1 gene promoter occur in 5–8% of healthy individuals and are associated with a significantly elevated risk of breast and ovarian cancer. Similar events may also affect other tumor suppressor genes, potentially being a significant contributor to cancer bur...

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Detalles Bibliográficos
Autores principales: Nikolaienko, Oleksii, Lønning, Per Eystein, Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622323/
https://www.ncbi.nlm.nih.gov/pubmed/37919976
http://dx.doi.org/10.1093/gigascience/giad087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622323/
https://www.ncbi.nlm.nih.gov/pubmed/37919976
http://dx.doi.org/10.1093/gigascience/giad087

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