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Conformational ensemble-dependent lipid recognition and segregation by prenylated intrinsically disordered regions in small GTPases
We studied diverse prenylated intrinsically disordered regions (PIDRs) of Ras and Rho family small GTPases using long timescale atomistic molecular dynamics simulations in an asymmetric model membrane of phosphatidylcholine (PC) and phosphatidylserine (PS) lipids. Here we show that conformational pl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622456/ https://www.ncbi.nlm.nih.gov/pubmed/37919400 http://dx.doi.org/10.1038/s42003-023-05487-6 |