Deep brain stimulation of thalamic nucleus reuniens promotes neuronal and cognitive resilience in an Alzheimer’s disease mouse model

The mechanisms that confer cognitive resilience to Alzheimer’s Disease (AD) are not fully understood. Here, we describe a neural circuit mechanism underlying this resilience in a familial AD mouse model. In the prodromal disease stage, interictal epileptiform spikes (IESs) emerge during anesthesia i...

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Detalles Bibliográficos
Autores principales: Shoob, Shiri, Buchbinder, Nadav, Shinikamin, Ortal, Gold, Or, Baeloha, Halit, Langberg, Tomer, Zarhin, Daniel, Shapira, Ilana, Braun, Gabriella, Habib, Naomi, Slutsky, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622498/
https://www.ncbi.nlm.nih.gov/pubmed/37919286
http://dx.doi.org/10.1038/s41467-023-42721-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622498/
https://www.ncbi.nlm.nih.gov/pubmed/37919286
http://dx.doi.org/10.1038/s41467-023-42721-5

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