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A fluorogenic, peptide-based probe for the detection of Cathepsin D in macrophages

Cathepsin D is a protease that is an effector in the immune response of macrophages, yet to date, only a limited number of probes have been developed for its detection. Herein, we report a water soluble, highly sensitive, pH insensitive fluorescent probe for the detection of Cathepsin D activity tha...

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Detalles Bibliográficos
Autores principales: Rodriguez-Rios, Maria, McHugh, Brian J., Liang, Zhengqi, Megia-Fernandez, Alicia, Lilienkampf, Annamaria, Dockrell, David, Bradley, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622513/
https://www.ncbi.nlm.nih.gov/pubmed/37919467
http://dx.doi.org/10.1038/s42004-023-01035-9