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A fluorogenic, peptide-based probe for the detection of Cathepsin D in macrophages
Cathepsin D is a protease that is an effector in the immune response of macrophages, yet to date, only a limited number of probes have been developed for its detection. Herein, we report a water soluble, highly sensitive, pH insensitive fluorescent probe for the detection of Cathepsin D activity tha...
Autores principales: | Rodriguez-Rios, Maria, McHugh, Brian J., Liang, Zhengqi, Megia-Fernandez, Alicia, Lilienkampf, Annamaria, Dockrell, David, Bradley, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622513/ https://www.ncbi.nlm.nih.gov/pubmed/37919467 http://dx.doi.org/10.1038/s42004-023-01035-9 |
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