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Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer

Sarcomatoid Urothelial Bladder Cancer (SARC) is a rare and aggressive histological subtype of bladder cancer for which therapeutic options are limited and experimental models are lacking. Here, we report the establishment of a long-term 3D organoid-like model derived from a SARC patient (SarBC-01)....

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Detalles Bibliográficos
Autores principales: Garioni, Michele, Tschan, Viviane J., Blukacz, Lauriane, Nuciforo, Sandro, Parmentier, Romuald, Roma, Luca, Coto-Llerena, Mairene, Pueschel, Heike, Piscuoglio, Salvatore, Vlajnic, Tatjana, Stenner, Frank, Seifert, Hans-Helge, Rentsch, Cyrill A., Bubendorf, Lukas, Le Magnen, Clémentine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622543/
https://www.ncbi.nlm.nih.gov/pubmed/37919480
http://dx.doi.org/10.1038/s41698-023-00466-w