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Chloroplast transformation for bioencapsulation and oral delivery using the immunoglobulin G fragment crystallizable (Fc) domain

Proinsulin Like Growth Factor I (prolGF-I) and myostatin (Mstn) regulate muscle regeneration and mass when intravenously delivered. We tested if chloroplast bioencapsulated forms of these proteins may serve as a non-invasive means of drug delivery through the digestive system. We created tobacco (Ni...

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Detalles Bibliográficos
Autores principales: LaManna, Lisa, Chou, Chih-Hsuan, Lei, Hanqin, Barton, Elisabeth R., Maliga, Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622566/
https://www.ncbi.nlm.nih.gov/pubmed/37919321
http://dx.doi.org/10.1038/s41598-023-45698-9