Targeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancer

Lung cancer is the leading cause of cancer-related mortality worldwide. CNOT3, a subunit of the CCR4-NOT complex, has recently been suggested to be overexpressed in lung cancer and involved in tumor malignancy. However, its precise role and the underlying mechanisms still need to be fully revealed....

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Detalles Bibliográficos
Autores principales: Jing, Lin, Zhai, Meng-En, Qian, Mei-Rui, Li, Yi-Ming, Han, Ming-Wei, Wang, Kun, Huang, Wan, Nan, Gang, Jiang, Jian-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622567/
https://www.ncbi.nlm.nih.gov/pubmed/37919290
http://dx.doi.org/10.1038/s41420-023-01701-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622567/
https://www.ncbi.nlm.nih.gov/pubmed/37919290
http://dx.doi.org/10.1038/s41420-023-01701-w

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