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Targeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancer
Lung cancer is the leading cause of cancer-related mortality worldwide. CNOT3, a subunit of the CCR4-NOT complex, has recently been suggested to be overexpressed in lung cancer and involved in tumor malignancy. However, its precise role and the underlying mechanisms still need to be fully revealed....
Autores principales: | Jing, Lin, Zhai, Meng-En, Qian, Mei-Rui, Li, Yi-Ming, Han, Ming-Wei, Wang, Kun, Huang, Wan, Nan, Gang, Jiang, Jian-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622567/ https://www.ncbi.nlm.nih.gov/pubmed/37919290 http://dx.doi.org/10.1038/s41420-023-01701-w |
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