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Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time

SARS-CoV-2 neutralising antibodies provide protection against COVID-19. Evidence from early vaccine trials suggested binding antibody thresholds could serve as surrogate markers of neutralising capacity, but whether these thresholds predict sufficient neutralising capacity against variants of concer...

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Detalles Bibliográficos
Autores principales: Kenny, Grace, O’Reilly, Sophie, Wrigley Kelly, Neil, Negi, Riya, Gaillard, Colette, Alalwan, Dana, Saini, Gurvin, Alrawahneh, Tamara, Francois, Nathan, Angeliadis, Matthew, Garcia Leon, Alejandro Abner, Tinago, Willard, Feeney, Eoin R., Cotter, Aoife G., de Barra, Eoghan, Yousif, Obada, Horgan, Mary, Doran, Peter, Stemler, Jannik, Koehler, Philipp, Cox, Rebecca Jane, O’Shea, Donal, Olesen, Ole F., Landay, Alan, Hogan, Andrew E., Lelievre, Jean-Daniel, Gautier, Virginie, Cornely, Oliver A., Mallon, Patrick W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622572/
https://www.ncbi.nlm.nih.gov/pubmed/37919289
http://dx.doi.org/10.1038/s41467-023-42717-1