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Intronic Variants of the Angiotensin-Converting Enzyme 2 Gene Modulate Plasma ACE2 Levels and Possibly Confer Protection against Severe COVID-19

Membrane-bound angiotensin-converting enzyme 2 (ACE2) receptor acts as the entry point for the novel coronavirus, SARS-CoV-2. Polymorphisms in the ACE2 gene may alter viral binding, regulate the expression of ACE2, and thus, affect disease severity. In this study, 68 COVID-19 patients with varying d...

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Detalles Bibliográficos
Autores principales: Ahmed, Rubaiat, Saba, Abdullah Al, Paul, Anik, Nur, Jasmin, Alam, Md Sohrab, Chakraborty, Sajib, Howlader, Md. Zakir Hossain, Islam, Laila N., Nabi, A. H. M. Nurun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622595/
https://www.ncbi.nlm.nih.gov/pubmed/37929242
http://dx.doi.org/10.1155/2023/5705076