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ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice

OBJECTIVE: Pro-inflammatory polarization of adipose tissue macrophages (ATMs) plays a critical role in the pathogenesis of obesity-associated chronic inflammation. However, little is known about the role of lipids in the regulation of ATMs polarity and inflammation in response to metabolic stress. D...

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Detalles Bibliográficos
Autores principales: Poursharifi, P., Schmitt, C., Chenier, I., Leung, Y.H., Oppong, A.K., Bai, Y., Klein, L.-L., Al-Mass, A., Lussier, R., Abu-Farha, M., Abubaker, J., Al-Mulla, F., Peyot, M.-L., Madiraju, S.R.M., Prentki, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622714/
https://www.ncbi.nlm.nih.gov/pubmed/37838014
http://dx.doi.org/10.1016/j.molmet.2023.101822