A degron-based approach to manipulate Eomes functions in the context of the developing mouse embryo

The T-box transcription factor Eomesodermin (Eomes), also known as Tbr2, plays essential roles in the early mouse embryo. Loss-of-function mutant embryos arrest at implantation due to Eomes requirements in the trophectoderm cell lineage. Slightly later, expression in the visceral endoderm promotes a...

Descripción completa

Detalles Bibliográficos
Autores principales: Bisia, Alexandra M., Costello, Ita, Xypolita, Maria-Eleni, Harland, Luke T. G., Kurbel, Philipp J., Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622880/
https://www.ncbi.nlm.nih.gov/pubmed/37871215
http://dx.doi.org/10.1073/pnas.2311946120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622880/
https://www.ncbi.nlm.nih.gov/pubmed/37871215
http://dx.doi.org/10.1073/pnas.2311946120

Ejemplares similares