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NANOG expression in parthenogenetic porcine blastocysts is required for intact lineage specification and pluripotency

OBJECTIVE: Nanog homeobox (NANOG) is a core transcription factor that contributes to pluripotency along with octamer binding transcription factor-4 (OCT4) and sex determining region-Y box-2 (SOX2). It is an epiblast lineage marker in mammalian pre-implantation embryos and exhibits a species-specific...

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Detalles Bibliográficos
Autores principales: Lee, Mingyun, Oh, Jong-Nam, Choe, Gyung Cheol, Choi, Kwang-Hwan, Lee, Dong-Kyung, Kim, Seung-Hun, Jeong, Jinsol, Ahn, Yelim, Lee, Chang-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Animal Bioscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623019/
https://www.ncbi.nlm.nih.gov/pubmed/37641830
http://dx.doi.org/10.5713/ab.23.0210