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Myeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis

The pathogenesis of atherosclerosis is defined by impaired lipid handling by macrophages which increases intracellular lipid accumulation. This dysregulation of macrophages triggers the accumulation of apoptotic cells and chronic inflammation which contributes to disease progression. We previously r...

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Detalles Bibliográficos
Autores principales: Cao, DuoYao, Saito, Suguru, Xu, LiMin, Fan, Wei, Li, Xiaomo, Ahmed, Faizan, Jovanovic, Predrag, Shibata, Tomohiro, Che, Mingtian, Bernstein, Ellen A., Gianni, Jorge, Divakaruni, Ajit S., Okwan-Duodu, Derick, Khan, Zakir, Riera, Celine E., Chen, Fanfan, Bernstein, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623052/
https://www.ncbi.nlm.nih.gov/pubmed/37928535
http://dx.doi.org/10.3389/fimmu.2023.1278383