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PP2Ac knockdown attenuates lipotoxicity‑induced pancreatic β‑cell dysfunction and apoptosis

Protein phosphatase 2A (PP2A) is one of the most common serine/threonine phosphatases in mammalian cells, and it primarily functions to regulate cell signaling, glycolipid metabolism and apoptosis. The catalytic subunit of PP2A (PP2Ac) plays an important role in the functions of the protein. However...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengwei, Tong, Beier, Liu, Jie, Feng, Jieyuan, Song, Linyang, Wang, Huawei, Ke, Mengting, Xu, Chengkai, Xu, Yancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623214/
https://www.ncbi.nlm.nih.gov/pubmed/37928506
http://dx.doi.org/10.3892/etm.2023.12247