Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells

Sialic acid-binding immunoglobulin-like lectin (Siglec)-8 is a sialoside-binding receptor expressed by eosinophils and mast cells that exhibits priming status- and cell type-dependent inhibitory activity. On eosinophils that have been primed with IL-5, GM-CSF, or IL-33, antibody ligation of Siglec-8...

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Detalles Bibliográficos
Autores principales: Cao, Yun, Rische, Clayton H., Bochner, Bruce S., O’Sullivan, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623328/
https://www.ncbi.nlm.nih.gov/pubmed/37928558
http://dx.doi.org/10.3389/fimmu.2023.1283370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623328/
https://www.ncbi.nlm.nih.gov/pubmed/37928558
http://dx.doi.org/10.3389/fimmu.2023.1283370

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