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The SGK3-Catalase antioxidant signaling axis drives cervical cancer growth and therapy resistance

Cancer cells frequently exhibit aberrant redox homeostasis and adaptation to oxidative stress. Hence abrogation of redox adaptation in cancer cells can be exploited for therapeutic benefit. Here we report SGK3 functions as an anti-oxidative factor to promote cell growth and drug resistance in cervic...

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Detalles Bibliográficos
Autores principales: Wang, Min, Liu, Jiannan, Liao, Xingming, Yi, Yasong, Xue, Yijue, Yang, Ling, Cheng, Hailing, Liu, Pixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623367/
https://www.ncbi.nlm.nih.gov/pubmed/37866161
http://dx.doi.org/10.1016/j.redox.2023.102931