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Avicularin alleviates acute liver failure by regulation of the TLR4/MyD88/NF‐κB and Nrf2/HO‐1/GPX4 pathways to reduce inflammation and ferroptosis

Acute liver failure (ALF) is an inflammation‐mediated hepatocyte death process associated with ferroptosis. Avicularin (AL), a Chinese herbal medicine, exerts anti‐inflammatory and antioxidative effects. However, the protective effect of AL and the mechanism on ALF have not been reported. Our in viv...

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Detalles Bibliográficos
Autores principales: Shi, Pei, Zhu, Wentao, Fu, Jiwei, Liang, An, Zheng, Ting, Wen, Zhilong, Wu, Xincheng, Peng, Yuchen, Yuan, Songsong, Wu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623517/
https://www.ncbi.nlm.nih.gov/pubmed/37644784
http://dx.doi.org/10.1111/jcmm.17905